Evidence & Resources

Pharmacological Interventions May Slow Photoreceptor Degeneration

Antioxidants and Vitamin A derivatives may slow degeneration. Supportive, not curative.

Direct Cortical Stimulation May Restore Vision Without Functional Eyes

BCI efforts aim to stimulate visual cortex directly. Potential for complete bypass. Highly experimental.

Optogenetics Enables Non-Photoreceptor Cells to Respond to Light

Light-sensitive proteins introduced into retinal ganglion cells. Works even when photoreceptors are gone. Clinical proof...

Stem Cell-Derived Retinal Cells Can Replace Lost Photoreceptors

iPSC can be differentiated into retinal cells and transplanted. Does not depend on mutation type. Integration challenge.

CRISPR-Based Editing Can Modify Disease-Causing Mutations in Retina

Gene editing technologies such as CRISPR can directly modify mutations in retinal cells. Precision but still early-stage...

Gene Therapy Can Restore Function in Mutation-Specific RP Cases

Gene therapy using viral vectors (e.g., AAV) can introduce functional copies of defective genes into retinal cells. Work...