RPGR-Associated Retinal Degeneration in Human X-Linked RP and a Murine Model - PMC

Description

The faster degeneration rate in this model has been attributed to a gain-of-function mechanism.14 A different ORF15 transgene was introduced into the Rpgr-null mouse, resulting in preservation of ONL thickness and partial recovery of visual function when compared to WT at 14 months of age.58 The add

Source

Not linked to any hypothesis yet.